Core Active Rutin Powder NF11 / DAB10
Flos Sophorae Immaturus · 95%–101.5% · Yellow greenish microcrystalline powder
Sophora japonica L. (synonym Styphnolobium japonicum), predominantly sourced from the Qinling Mountain basin in Shaanxi, China, serves as the global industrial foundation for essential flavonoid monomers. Understanding the purity profile, molecular integrity, and supply chain dynamics is critical for commercial formulators in nutraceutical, functional cosmetic, and pharmaceutical manufacturing.

Our extraction yield begins with premium sun-dried unopened flower buds (Flos Sophorae Immaturus), ensuring native rutin content surpassing 18% prior to solvent extraction.
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High-purity quercetin-3-rutinoside extracted via non-toxic hydroalcoholic solvents, recrystallized for micro-vascular and antioxidant applications.
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Produced via clean catalytic hydrolysis of rutin. The gold standard dietary antioxidant with verified HPLC peak identity and free of bio-residual residues.
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Specialized etherification yields water-soluble Troxerutin (EP Grade), resolving bioavailability limitations in clinical phlebology and cosmeceutical formulations.
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Standardized Phytochemistry From dietary cellular defense supplements to cosmeceutical brightening serums, our product pipeline leverages the complete phytochemical matrix of Sophora Japonica flower buds. Every derivative is verified with multi-wavelength HPLC profiling to guarantee zero adulteration.
Engineered to assist procurement engineers and formulation specialists in matching chemical specifications with bioavailability and target dosage forms.
| Phytochemical Active | CAS Reg. No. | Assay Method | Standard Spec | Target Solubility | Primary Application |
|---|---|---|---|---|---|
| Rutin NF11 / EP | 153-18-4 | UV / HPLC | ≥95.0% - 101.5% | Sparingly soluble in H₂O; soluble in pyridine & alkali | Cardiovascular health, vascular fragility, venous insufficiency |
| Quercetin Dihydrate | 6151-25-3 | HPLC | ≥95.0% / ≥98.0% | Insoluble in cold water; soluble in ethanol, DMSO & oils | Senolytic complexes, immune defense, sports endurance stacks |
| Quercetin Anhydrous | 117-39-5 | HPLC | ≥98.0% | Moisture <4.0%; soluble in hot ethanol and alkaline solutions | Hard-shell two-piece capsules, moisture-sensitive tableting |
| Troxerutin EP | 7085-55-5 | HPLC | ≥80.0% (Tri-hydroxyethylrutin) | Freely soluble in water (100 mg/mL) | Ophthalmic drops, topical venotonic gels, cosmetic anti-redness |
| L-Rhamnose Monohydrate | 10030-85-0 | HPLC / Optical | ≥98.0% | Freely soluble in water | Anti-glycation anti-aging skincare, chiral synthesis, flavor synthesis |
E-E-A-T Sourcing Note from Shaanxi Torzi Biotech Co., Ltd. Quality Control: Many commercial suppliers quote Quercetin assayed strictly by UV spectrophotometry, which fails to distinguish between quercetin, isorhamnetin, and intermediate degradants. We advise global QA specialists to validate purchases strictly by HPLC against reference standard USP/EP runs to prevent non-compliant assay discrepancies.
In-stock inventory packed in food-grade fiber drums, fully validated by internal HPLC and atomic absorption spectrophotometry.
Core Active Flos Sophorae Immaturus · 95%–101.5% · Yellow greenish microcrystalline powder
High Demand Hydrolytic cleavage derivative · ≥98.0% HPLC · Heavy Metals <10ppm
Water Soluble Hydroxyethylated Rutin · Freely Water Soluble · Yellow-green powder
Cosmetic Grade Natural monosaccharide by-product · ≥98.0% HPLC · Anti-wrinkle active
The botanical extract landscape is moving rapidly toward tighter regulatory controls, enhanced delivery mechanics, and circular manufacturing. Procurement executives must evaluate these 4 macroeconomic vectors when contracting Sophora japonica supplies.
Native Quercetin exhibits notoriously poor oral absorption (<2%). Forward-thinking brands are shifting purchase contracts toward micronized grades (d90 < 20μm), liposomal quercetin platforms, and cyclodextrin complexation to achieve 20x to 50x plasma concentration multiples in dietary finished goods.
European border controls (EU Regulation 2015/1933) and FDA cGMP audits increasingly reject lots containing trace polycyclic aromatic hydrocarbons (PAH4 > 10ppb) or ethylene oxide sterilants. Torzi Biotech has engineered low-temperature drying protocols that guarantee zero thermal degradation and complete EtO absence.
Traditional acidic hydrolysis generates substantial effluent. The future lies in enzymatic cleavage of rutin to yield Quercetin and L-Rhamnose simultaneously without synthetic inorganic acids. Shaanxi Torzi Biotech Co., Ltd. continuously expands solvent-recovery and water treatment operations for sustainable procurement.
Direct price-lock agreements against seasonal raw bud harvest fluctuations. Inquire about customized packaging, bulk delivery schedules, and regulatory documentation packs (COA, TSE/BSE, Non-GMO, Allergen statements).
At Shaanxi Torzi Biotech Co., Ltd., every kilogram of Sophora Japonica Extract is subjected to rigorous bench testing. We verify HPLC chromatographic purity, quantitative loss on drying, ash levels, and trace heavy metals via atomic absorption, ensuring compliance with global pharmacopoeial monographs (USP, EP, DAB, CP).
| Monograph Parameter | Rutin (NF11 / EP) | Quercetin Dihydrate (HPLC 98%) | Quercetin Anhydrous | Troxerutin EP |
|---|---|---|---|---|
| Identification | Positive by TLC & HPLC Retention | Conforms to USP/EP RS | Matches Standard RT | IR & HPLC Conforms |
| Assay (on dry basis) | 95.0% – 101.5% | ≥98.0% HPLC | ≥98.0% HPLC | ≥80.0% Tri-HE-rutin |
| Loss on Drying | 5.5% – 9.0% | 9.5% – 12.0% | ≤4.0% | ≤4.5% |
| Sulfated Ash | ≤0.3% | ≤0.1% | ≤0.1% | ≤0.4% |
| Heavy Metals (Pb, Cd, Hg, As) | Lead <2ppm, Arsenic <1ppm | Total <10ppm (AAS/AFS) | Total <10ppm (AAS/AFS) | Total <10ppm |
| Residual Solvents | Meets USP <467> (Ethanol only) | Ethanol <5000ppm; Methanol Nil | Complies with EP Class 2/3 | Ethylene Glycol <620ppm |
Shaanxi Torzi Biotech Co., Ltd. is positioned at the epicentre of botanical extraction in Xi'an, China. With 12,447 m² of specialized production and storage space, our facilities provide unbroken chain-of-custody, end-to-end analytical traceability, and large-scale industrial consistency.
Every lot undergoes rigid in-process checks before moving from extraction tanks to spray towers and final packaging cleanrooms.








Dedicated stainless steel extraction, concentration, reaction, and drying machinery designed to prevent cross-contamination.












Our internal analytical laboratory guarantees that no material departs without complete chemical and toxicological qualification.








Real images from our factory floor, warehouse staging bays, and international global trade delegations.








Shaanxi Torzi Biotech Co., Ltd. eliminates regulatory risk for multinational importers. We supply fully documented technical files including Master DMFs, COAs, Non-GMO affidavits, and third-party laboratory confirmations.

Ecological harvesting
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Global Islamic market compliance
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Strict purity standards
VerifiedOn-site supplier assessment
VerifiedQuality management system
VerifiedHPLC, GC, AAS screened
VerifiedEssential engineering and regulatory answers regarding Sophora Japonica Extract, Rutin NF11, Quercetin Dihydrate, Troxerutin, and custom processing.
The primary difference lies in the crystal hydrate structure and moisture content. Quercetin Dihydrate contains two molecules of water of crystallization, resulting in a theoretical moisture content of approximately 9.5% to 12.0%. Quercetin Anhydrous undergoes vacuum desiccation to reduce moisture below 4.0%. For standard dietary capsules, dihydrate is the industry standard; for moisture-sensitive formulas or high-density tableting where moisture causes capping or degradative instability, Quercetin Anhydrous is specified.
Shaanxi Torzi Biotech Co., Ltd. operates high-performance liquid chromatography (HPLC) with diode-array detection (DAD) at 254nm and 370nm. We do not rely exclusively on spectrophotometric UV titration, which is non-specific and easily fooled by secondary polyphenols. We quantify retention time against authentic primary reference standards (USP/EP) and verify related substances (such as kaempferol, isorhamnetin, and unreacted rutin) to guarantee strict botanical purity.
We use dedicated aqueous ethanol (food grade) extraction systems. We strictly forbid chlorinated hydrocarbons, such as dichloromethane or chloroform, commonly used by discount processors. Residual ethanol is kept well below USP <467> and EP limits (<5,000 ppm) via rotary evaporation and vacuum drying ovens, and is verified by headspace Gas Chromatography (GC).
Yes. Our pulverizing and sieving workshops can deliver standard 80-mesh powder, 100-mesh, and air-jet micronized powders with particle size distributions targeting d90 < 20 μm. Micronization improves dissolution kinetics and suspension stability in softgels and RTD dry-blend formulations.
Our standard MOQ for Sophora japonica extract derivatives (Rutin, Quercetin, Troxerutin) is 25 kg, packaged in double-polyethylene food-grade bags sealed inside round fiber drums. For validation runs, formulation trials, or R&D piloting, we provide sample dispatch batches of 1 kg to 5 kg upon request.
Yes. In full accordance with EU Regulation (EU) 2015/1933, our Sophora Japonica extracts are tested for Benzo(a)pyrene (<10 μg/kg) and the sum of PAH4 (<50 μg/kg). Furthermore, our factory enforces zero-Ethylene Oxide (EtO) handling and zero gamma-irradiation protocols, satisfying the strictest European and North American retail audits.
Reach out directly to the manufacturer. Receive full batch COAs, chromatograms, and competitive Tier-1 factory pricing.